Choline metabolism in pneumococci
نویسندگان
چکیده
منابع مشابه
Choline Metabolism: Meaning and Significance
Choline is an essential nutrient Choline (Cho), a quaternary amine, is an essential nutrient supplied by the diet (1, 2). Choline uptake and intracellular metabolism during the prenatal period were shown to have a critical role in brain development and cognitive processes (3, 4). Choline is a precursor in several key biochemical pathways as demonstrated below in scheme 1. Scheme 1: Metabolic Fa...
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Single nucleotide polymorphisms (SNPs) in choline metabolizing genes are associated with disease risk and greater susceptibility to organ dysfunction under conditions of dietary choline restriction. However, the underlying metabolic signatures of these variants are not well characterized and it is unknown whether genotypic differences persist at recommended choline intakes. Thus, we sought to d...
متن کاملProtein metabolism in the choline-deficient rat. I. Effect of choline on serum proteins.
Unless the choline content is sufficient to supply all of the required methyl groups, the amount of choline in a diet apparently determines the quantity of methionine used for protein synthesis and the quantity reserved for use as a methyl donor. This concept is supported by Treadwell’s demonstration (1) of the growth-stimulating effect of choline and Salmon’s observation (2) that the nutritive...
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Cancer cells have distinct metabolomic profile. Metabolic enzymes regulate key oncogenic signaling pathways and have an essential role on tumor progression. Here, serum metabolomic analysis was performed in 45 patients with T-cell lymphoma (TCL) and 50 healthy volunteers. The results showed that dysregulation of choline metabolism occurred in TCL and was related to tumor cell overexpression of ...
متن کاملMaternal choline intake modulates maternal and fetal biomarkers of choline metabolism in humans.
BACKGROUND In 1998 choline Adequate Intakes of 425 and 450 mg/d were established for nonpregnant and pregnant women, respectively. However, to our knowledge, no dose-response studies have been conducted to evaluate the effects of pregnancy or maternal choline intake on biomarkers of choline metabolism. OBJECTIVE We sought to quantify the effects of pregnancy and maternal choline intake on mat...
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ژورنال
عنوان ژورنال: Journal of Bacteriology
سال: 1977
ISSN: 0021-9193,1098-5530
DOI: 10.1128/jb.130.1.571-574.1977